Postdoctoral Fellow-MSH-32074-063

Description Salary: $74,692   Department: Cardiovascular Research Institute   Physical work location:  1470 Madison Ave, Hess Bldg, 7th Fl, New York, NY 10029   Name PI or Supervisor:  Cameron McAlpine, [phone in the portal], [contact in the portal]   Web link to Lab: [link in the portal]   Web link to Department: [link in the portal]   Administrative Contact: (phone and email) Mikaela Walcott, [contact in the portal] , [phone in the portal] Responsibilities   Details of Research Project:    Title: Evaluate neuronal control of macrophage function in the heart.  The candidate will use fundamental science tools to test how the nervous system regulates macrophage function and biology in the heart. The candidate will test how neurotransmitters and neuropeptides modify macrophage subsets and inflammatory processes in the heart and its vasculature at steady state, after myocardial infarction, during atherosclerosis, or in the context of other cardiovascular pathologies.      Technical Duties: (include any protocols)   Technical duties will include mouse modeling and handling, flow cytometry, advance confocal imaging of the heart, single cell sequencing, and neuronal manipulation methods like neuronal ablation, neuropeptide deletion, and brain circuit manipulation. Molecular assays like protein quantification or mRNA expression. Qualifications   Educational and other Requirements for the position: PhD   Experience Required: 0   Goals/Outcomes of the Research Project:  We will identify new ways by which the nervous system regulates inflammation in the cardiovascular system. Novel signaling mechanisms will be further developed and tested for therapeutic intervention.   , J16 - Cardiovascular Research Institute - ISM, Icahn School of Medicine Employer Description Strength through Unity and Inclusion The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual. At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. 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